Respect for your privacy is our priority

The cookie is a small information file stored in your browser each time you visit our web page.

Cookies are useful because they record the history of your activity on our web page. Thus, when you return to the page, it identifies you and configures its content based on your browsing habits, your identity and your preferences.

You may accept cookies or refuse, block or delete cookies, at your convenience. To do this, you can choose from one of the options available on this window or even and if necessary, by configuring your browser.

If you refuse cookies, we can not guarantee the proper functioning of the various features of our web page.

For more information, please read the COOKIES INFORMATION section on our web page.

Refuse

News

Lycored study: Active nutrients work synergistically

29/10/2019 - François-Xavier Branthôme

Tomato nutrient complex beats synthetic lycopene for blood pressure benefits

Lycored's tomato nutrient complex may lower blood pressure in untreated hypertensive people, while synthetic lycopene alone had no effect, says a new double-blind, randomized dose-response study from Israel,
The study, published in Nutrients, found that eight weeks of consuming a tomato nutrient complex containing 15 mg of lycopene led to average decreases in systolic blood pressure (SBP) and diastolic blood pressure (DBP) of 10 mm Hg and 5 mm Hg respectively.
On the other hand, no changes to blood pressure were observed at lower doses of the tomato nutrient complex, or for 15 mg of synthetic lycopene, or for placebo, reported scientists from Ben-Gurion University of the Negev and Lycored.

According to Lycored, which funded the study, this is the fourth in a series of human clinical trials on the product's benefits as a holistic solution contributing to overall cardiometabolic health. This clinical program helped Lycored create Cardiomato, its cardio-optimized carefully calibrated patented composition, said the company,
“This research reflects the evolution of our cardio-metabolic journey," said Dr Karin Hermoni, head of science and nutrition at Lycored. "One of its aims was to compare the effects on blood pressure of pure synthetic lycopene as a standalone with that of the entire nutrient and carotenoid mixture from the tomato. The results suggest that the myriad active nutrients our extract contains work synergistically to drive significant benefits.
This study provides tangible evidence supporting the dose of tomato phytonutrients, and specifically of lycopene, that we recommend to deliver benefits for cardio-metabolic health. These results are only pan of a full program examining the bioavailability and efficacy of tomato phytonutrients”.

Inclusion in the daily diet of lycopene-rich foods such as tomato products is recommended
The researchers recruited 61 people aged between 35 and 60 and with systolic blood pressure between 130 and 140 mmHg. Participants were randomly assigned to receive capsules containing tomato nutrient complex standardized for 5, 15 or 30mg of lycopene (and containing all the rest of the tomato phytonutrients), pure lycopene, or a placebo to consume with their main meal for eight weeks.
The results showed that both tomato nutrient complex groups with 15 or 30mg of lycopene experienced statistically significant reductions in blood pressure over the course of the study, but no effects were reported for the other groups.
"One explanation for the lower efficacy of the synthetic lycopene is the presence of other active nutrients in the tomato extract preparation” wrote the researchers. "Indeed, in a previous study [Linnewiel-Hermoni et al., Arch. Biochem. Biophys. 2075, Vol. 572, pp. 28-35], we found that the anti-cancer effects of carotenoids and other phytonutrients present in tomato extract (e.g., lycopene, phytoene and phytofluene) resides in their combined activity, which is synergistically higher than the activity of each compound alone."
A subset of 27 subjects continued the supplementation regimen for an additional four months, with results showing significant reductions in systolic blood pressure at all points.
Commenting on the doses, the researchers noted that raw tomatoes typically contain between 2.5 and 4 mg of lycopene per 100 grams of fruit, and therefore a "reasonable consumption of tomatoes" of 100 to 200 grams per day would provide a lycopene dose of between 4 and 8 mg of lycopene, which would be an insufficient dose to elicit a reduction in systolic blood pressure.
"Therefore, inclusion in the daily diet of other lycopene-rich foods such as tomato products and supplements is recommended, "they wrote.

Full study:
"Effect of Tomato Nutrient Complex on Blood Pressure: A Double Blind, Randomized Dose-Response Study", Authors: T. Wolak et al. Nutrients, 11 (5)r 950, doi: 10.3390/nul 1050950

Source: nutraingredients-usa

Related companies

Lycored

Tomato processor See details

Back

________________________________________

Editor : TOMATO NEWS SAS - MAISON DE L'AGRICULTURE - TSA 48449 - 84912 AVIGNON Cedex 9 - FRANCE
contact@tomatonews.com
www.tomatonews.co m

Supporting partners